Ukwahluka kobuhlanga nobuhlanga kwizilingo zeklinikhi zamayeza okuguqula izifo kwi-PD: Uhlolo olucwangcisiweyo 

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Kwiminyaka embalwa edlulileyo, uphuhliso lwezilingo zonyango ezigxile kunyango lokuguqula izifo luye lwaguqula uphando lwesifo sikaParkinson (PD), lugxininisa ekucothiseni ukuqhubela phambili kwesifo endaweni yokunyanga iimpawu nje kuphela. Nangona kunjalo, umbuzo obalulekileyo usasele: Ngubani ngokwenene omeleyo kwezi zilingo?  

Iqela lethu liphonononge kwaye lahlalutya idatha malunga nokwahlukana kweentlanga kunye nobuhlanga kwiimvavanyo zeklinikhi ezingacwangciswanga (ii-RCT) ukuze kufunyanwe unyango olunokwenzeka lwesifo sikaParkinson (PD). Sijonge iimvavanyo ezinkulu ezingama-37 zamazwe ngamazwe, ezingaboni kabini kunye nezilawulwa yi-placebo, ezinabathathi-nxaxheba abangaphezu kwe-11,000. Phantse isiqingatha sale mvavanyo asizange sixele ngohlanga okanye uhlanga, nto leyo eyenza kube nzima ukuvavanya umahluko kwimvelaphi yabathathi-nxaxheba. Zili-19 kuphela kwizifundo ezingama-37 (51.4%) ezabelane ngolwazi malunga nohlanga okanye uhlanga lwabathathi-nxaxheba. Kwezi zifundo, uninzi lwabathathi-nxaxheba lwalumhlophe, kwaye zingama-251 kuphela kwi-5,735 (4.38%) ezazingengomhlophe. Uhlalutyo lwabathathi-nxaxheba abangengobamhlophe belulolu hlobo lulandelayo: Ama-Asia enza ama-61.4% kubathathi-nxaxheba abangama-251 abangengobamhlophe, abamnyama babe ngama-20.3%, amaHispanic abe ngama-7.6%, amaHawaii angama-0.4%, amaNdiya aseMelika/amaAlaska abe ngama-1.6%, kunye nezinye iintlanga/iintlanga ezahlukeneyo kwabangama-51 abaseleyo. Lilonke, abathathi-nxaxheba abamhlophe benze ama-98% abo bonke ababhalisele uvavanyo, bebonke bengabantu abayi-10,888.  

Ezi ziphumo zixhalabisa kwaye zibalulekile kuba isifo sikaParkinson sichaphazela abantu abavela kuzo zonke iintlanga neentlanga. Ke ngoko, uvavanyo lweklinikhi kufuneka lubonise la maqela ahlukeneyo ukuqinisekisa ukuba unyango olutsha luyasebenza kumaqela ahlukeneyo. Ukuzalwa kwemfuza, ukuvezwa kwendalo, ukufikelela kwimpilo, kunye nezinto ezichaphazela impilo yoluntu zonke zichaphazela umngcipheko wesifo, ukuqhubela phambili, kunye nempendulo yonyango. Ukufunda abathathi-nxaxheba abahlukeneyo kunceda abaphandi baqonde umahluko kwaye kuqinisekisa ukuba iziphumo zophando ziyasebenza kwizigulana kunyango.  

Abaphandi, abaxhasi, ii-arhente zenkxaso-mali, iingcali zezempilo, imibutho yokuxhasa izigulana, kunye noluntu kufuneka basebenzisane ukuphucula ulwahlulo kwizifundo zonyango zesifo sikaParkinson. Amaqhinga anjengobudlelwane boluntu, ukuqesha abantu abathetha iilwimi ezininzi, inkxaso-mali, kunye neendawo zophando ezifikelelekayo zinokuba ziindlela ezinokwenzeka zokunciphisa imiqobo yokubandakanyeka. Njengoko unyango olutsha nolusebenzayo lutshintshela kwindlela yokusebenza kwezonyango, ukuqinisekisa ukumelwa ngokupheleleyo kwizilingo kubalulekile. Ukumelwa okungcono kwenza uphando lube nobulungisa, komeleza ubungqina, kwaye kwenza unyango lube nokubaluleka ngakumbi kuluntu lwehlabathi lweParkinson. 

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